Book Hotels in Southwest Illinois, IL

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Top Southwest Illinois hotels

Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon

3 out of 5
145 North 44th Street , Mount Vernon, IL
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $106 total per night from Oct 5 to Oct 6
$106 total
Oct 5 - Oct 6
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
"Lady at the front desk at check in was very kind and polite."

Reviewed on Sep 27, 2025

Opens in a new windowDrury Plaza Hotel Mt. Vernon
The Principal Hotel

The Principal Hotel

3.5 out of 5
310 S Main St, Columbia, IL
Fully refundableReserve now, pay when you stay
$103 nightly
The price is $115 total per night from Oct 5 to Oct 6
$115 total
Oct 5 - Oct 6
Total with taxes and fees
A restaurant and a gym are featured at this hotel. Free self parking, a coffee shop, and dry cleaning are also offered.
"Everything was good. It is very clean. We had a couple of issues but the young lady at the front desk went above and beyond to take care of it. When really it wasn’t a big enough issue to worry about we just wanted to let her know for the next person in line. They have amazing staff and an amazing ..."

Reviewed on Sep 17, 2025

Opens in a new windowThe Principal Hotel
Drury Inn & Suites Marion

Drury Inn & Suites Marion

3 out of 5
2706 W DeYoung St, Marion, IL
Fully refundableReserve now, pay when you stay
$65 nightly
The price is $78 total per night from Oct 5 to Oct 6
$78 total
Oct 5 - Oct 6
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
"I’d give this hotel 10 stars! Great service, food, drinks, cheerful staff, comfortable room. Highly recommend!"

Reviewed on Sep 24, 2025

Opens in a new windowDrury Inn & Suites Marion
Drury Inn & Suites St. Louis Fairview Heights

Drury Inn & Suites St. Louis Fairview Heights

3 out of 5
12 Ludwig Dr, Fairview Heights, IL
Fully refundableReserve now, pay when you stay
$93 nightly
The price is $106 total per night from Oct 2 to Oct 3
$106 total
Oct 2 - Oct 3
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
Housekeeping problem
"They need to teach the housekeeping staff to not park their carts in the middle of the hallway. This makes it really hard to navigate the hallway with luggage."

Reviewed on Sep 18, 2025

Opens in a new windowDrury Inn & Suites St. Louis Fairview Heights
Best Western Plus Pontoon Beach

Best Western Plus Pontoon Beach

3 out of 5
4 Regency Pkwy, Granite City, IL
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $100 total per night from Sep 30 to Oct 1
$100 total
Sep 30 - Oct 1
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
"Great breakfast options. The hotel was clean and quiet."

Reviewed on Sep 22, 2025

Opens in a new windowBest Western Plus Pontoon Beach
Red Lion Inn & Suites Pontoon Beach

Red Lion Inn & Suites Pontoon Beach

2.5 out of 5
1240 E Chain Of Rocks Rd, Granite City, IL
Fully refundableReserve now, pay when you stay
$64 nightly
The price is $71 total per night from Oct 1 to Oct 2
$71 total
Oct 1 - Oct 2
Total with taxes and fees
This hotel features free WiFi in public areas, laundry facilities, and free self parking. Enjoy the free continental breakfast each morning. Staff at the 24-hour ...
"Very clean, friendly, delicious breakfast, highly recommended"

Reviewed on Sep 22, 2025

Opens in a new windowRed Lion Inn & Suites Pontoon Beach
Quality Inn & Suites near St. Louis and I-255

Quality Inn & Suites near St. Louis and I-255

2.5 out of 5
1607 Pontiac Dr, East St. Louis, IL
Fully refundableReserve now, pay when you stay
$69 nightly
The price is $78 total per night from Oct 26 to Oct 27
$78 total
Oct 26 - Oct 27
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
"Great hotel for the price"

Reviewed on Sep 21, 2025

Opens in a new windowQuality Inn & Suites near St. Louis and I-255
Super 8 by Wyndham O'Fallon

Super 8 by Wyndham O'Fallon

2 out of 5
1100 Eastgate Dr, O'Fallon, IL
Fully refundableReserve now, pay when you stay
$51 nightly
The price is $59 total per night from Oct 5 to Oct 6
$59 total
Oct 5 - Oct 6
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
"Amazing"

Reviewed on Sep 17, 2025

Opens in a new windowSuper 8 by Wyndham O'Fallon
La Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis

La Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis

3 out of 5
136 Regency Park, O'Fallon, IL
Fully refundableReserve now, pay when you stay
$71 nightly
The price is $82 total per night from Oct 26 to Oct 27
$82 total
Oct 26 - Oct 27
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
"Room was clean, staff friendly and helpful."

Reviewed on Sep 25, 2025

Opens in a new windowLa Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Cheap Southwest Illinois hotels

Motel 6 Caseyville, IL - Caseyville Il

Motel 6 Caseyville, IL - Caseyville Il

2431 Old Country Inn Dr, Caseyville, IL
$62 nightly
The price is $70 total per night from Sep 30 to Oct 1
$70 total
Sep 30 - Oct 1
Total with taxes and fees
6.2/10 (1,013 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Recent Southwest Illinois hotel reviews by fellow wanderers

Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon

5 out of 5
Posted 1 day ago
Travelocity Verified Review
"Lady at the front desk at check in was very kind and polite. "
A verified traveler from speedwell stayed at Drury Plaza Hotel Mt. Vernon
Drury Plaza Hotel Mt. Vernon
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