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Top Southwest Illinois hotels
Drury Plaza Hotel Mt. Vernon
145 North 44th Street Mount Vernon IL
Fully refundableReserve now, pay when you stay
$110 nightly
The price is $124 total per night from Oct 26 to Oct 27
$124 total
Oct 26 - Oct 27
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
"I only stay at Drury Inns. I plan my bi-annual trips to Florida and returning to Minnesota. I always get to Mount Vernon on the first day and to Marietta on the second day. It’s my favorite hotel and I have told this to everyone when they ask where I stay."
Reviewed on Oct 18, 2026
The Principal Hotel
310 S Main St Columbia IL
Fully refundableReserve now, pay when you stay
$109 nightly
The price is $121 total per night from Oct 20 to Oct 21
$121 total
Oct 20 - Oct 21
Total with taxes and fees
A restaurant and a gym are featured at this hotel. Free self parking, a coffee shop, and dry cleaning are also offered.
"It is new clean and easy to get to."
Reviewed on Oct 18, 2026
Drury Inn & Suites St. Louis Fairview Heights
12 Ludwig Dr Fairview Heights IL
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $102 total per night from Nov 1 to Nov 2
$102 total
Nov 1 - Nov 2
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
"We were very satisfied with our stay. Staff was friendly, courteous and helpful. The room was clean and bed and pillows were very comfortable. They had 5:30 enjoy your stay with drinks and food. After checking in, delicious as well as breakfast in the morning. Wonderful stay and will be back."
Reviewed on Oct 17, 2026
Comfort Inn Edwardsville - St. Louis
3080 S State Route 157 Edwardsville IL
Fully refundable
$89 nightly
The price is $103 total per night from Oct 26 to Oct 27
$103 total
Oct 26 - Oct 27
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. There's no skimping on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. ...
"Great hotel - Nice location, clean, quick check-in, hot breakfast. The only downside was that the A/C didn’t work right."
Reviewed on Oct 18, 2026
Best Western St. Louis Fairview Heights
150 Ludwig Dr Fairview Heights IL
Fully refundableReserve now, pay when you stay
$88 nightly
The price is $100 total per night from Oct 21 to Oct 22
$100 total
Oct 21 - Oct 22
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
"Nice hotel for a night's stay. Front desk staff very attentive to provide items we needed. Older than some hotels, but nice with several good restaurants and stores close by."
Reviewed on Oct 19, 2026
Super 8 by Wyndham O'Fallon
1100 Eastgate Dr O'Fallon IL
$53 nightly
The price is $61 total per night from Nov 1 to Nov 2
$61 total
Nov 1 - Nov 2
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
"I had a very short overnight stay with my daughter prior to softball games the next day. We arrived at about 11:00pm, and were gone by 6:00am. But that short time was long enough to make me realize - you get what you pay for. I just wanted a cheap room, as we were gonna simply sleep and leave. I ..."
Reviewed on Oct 18, 2026
Motel 6 Caseyville, IL - Caseyville Il
2431 Old Country Inn Dr Caseyville IL
Fully refundable
$59 nightly
The price is $67 total per night from Oct 21 to Oct 22
$67 total
Oct 21 - Oct 22
Total with taxes and fees
A seasonal outdoor pool, free self parking, and laundry facilities are featured at this motel. WiFi in public areas is free. A snack bar/deli is provided and ...
"Terrible smell as I walked into lobby...staff mopping floor w/dirty mop leaving an odor. Building is in needs of some paint & repairs. However room was clean..bed comfy..and quiet. Staff member was pleasant when i was checked in"
Reviewed on Oct 18, 2026
Drury Inn & Suites St. Louis O'Fallon, IL
1118 Central Park Drive O'Fallon IL
Fully refundableReserve now, pay when you stay
$101 nightly
The price is $117 total per night from Nov 15 to Nov 16
$117 total
Nov 15 - Nov 16
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
Quality Inn & Suites near St. Louis and I-255
1607 Pontiac Dr East St. Louis IL
Fully refundable
$73 nightly
The price is $83 total per night from Nov 11 to Nov 12
$83 total
Nov 11 - Nov 12
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
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See all available properties in Southwest Illinois
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Cheap Southwest Illinois hotels
Motel 6 Caseyville, IL - Caseyville Il
2431 Old Country Inn Dr Caseyville IL
$59 nightly
The price is $67 total per night from Oct 21 to Oct 22
$67 total
Oct 21 - Oct 22
Total with taxes and fees
6.4/10 (1,001 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in Southwest Illinois with star-rating
Check Southwest Illinois Hotels by Star Rating
4 Star Hotels
3 properties
Recent Southwest Illinois hotel reviews by fellow wanderers
Best Western St. Louis Fairview Heights
4 out of 5
Posted 3 hours ago
Travelocity Verified Review
"Nice hotel for a night's stay. Front desk staff very attentive to provide items we needed. Older than some hotels, but nice with several good restaurants and stores close by."
A verified traveler stayed at Best Western St. Louis Fairview Heights
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