Book Hotels in Southwest Illinois, IL
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Top Southwest Illinois hotels
Drury Plaza Hotel Mt. Vernon
145 North 44th Street Mount Vernon IL
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $106 total per night from Nov 30 to Dec 1
$106 total
Nov 30 - Dec 1
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
Everything was clean, breakfast was stupendous with tons of options, the staff were all very helpful and attentive. We had a perfect stay.
Reviewed on Nov 16, 2025
Drury Inn & Suites St. Louis O'Fallon, IL
1118 Central Park Drive O'Fallon IL
Fully refundableReserve now, pay when you stay
$102 nightly
The price is $118 total per night from Nov 30 to Dec 1
$118 total
Nov 30 - Dec 1
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
Great place
Reviewed on Nov 14, 2025
Drury Inn & Suites St. Louis Fairview Heights
12 Ludwig Dr Fairview Heights IL
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $106 total per night from Nov 24 to Nov 25
$106 total
Nov 24 - Nov 25
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
Staff was very nice and the room was clean and comfortable.
Reviewed on Nov 14, 2025
Comfort Suites Mount Vernon
404 South 44th Street Mount Vernon IL
Fully refundableReserve now, pay when you stay
$110 nightly
The price is $124 total per night from Nov 21 to Nov 22
$124 total
Nov 21 - Nov 22
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
Staff was so friendly. Room was very clean and comfortable. I would stay here again.
Reviewed on Nov 13, 2025
Best Western Plus Pontoon Beach
4 Regency Pkwy Granite City IL
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $95 total per night from Nov 30 to Dec 1
$95 total
Nov 30 - Dec 1
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
Everything was nice
Reviewed on Nov 10, 2025
Red Lion Inn & Suites Pontoon Beach
1240 E Chain Of Rocks Rd Granite City IL
Fully refundableReserve now, pay when you stay
$63 nightly
The price is $70 total per night from Nov 23 to Nov 24
$70 total
Nov 23 - Nov 24
Total with taxes and fees
This hotel features free WiFi in public areas, laundry facilities, and free self parking. Enjoy the free continental breakfast each morning. Staff at the 24-hour ...
Clean room
Reviewed on Nov 13, 2025
Quality Inn & Suites near St. Louis and I-255
1607 Pontiac Dr East St. Louis IL
Fully refundableReserve now, pay when you stay
$67 nightly
The price is $76 total per night from Nov 28 to Nov 29
$76 total
Nov 28 - Nov 29
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
Great
Reviewed on Nov 12, 2025
Super 8 by Wyndham O'Fallon
1100 Eastgate Dr O'Fallon IL
Fully refundableReserve now, pay when you stay
$47 nightly
The price is $54 total per night from Dec 7 to Dec 8
$54 total
Dec 7 - Dec 8
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
Rooms were spotless and fresh. Staff friendly and helpful.
Reviewed on Nov 16, 2025
La Quinta Inn & Suites by Wyndham Collinsville - St. Louis
6 Gateway Dr Collinsville IL
Fully refundableReserve now, pay when you stay
$76 nightly
The price is $87 total per night from Nov 23 to Nov 24
$87 total
Nov 23 - Nov 24
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
I paid the pet fee , there was no dog bags or empty waste basket for dog waste . Staff was friendly
Reviewed on Nov 13, 2025
Don't see what you're looking for?
See all available properties in Southwest Illinois
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Cheap Southwest Illinois hotels
Motel 6 Caseyville, IL - Caseyville Il
2431 Old Country Inn Dr Caseyville IL
$62 nightly
The price is $70 total per night from Nov 21 to Nov 22
$70 total
Nov 21 - Nov 22
Total with taxes and fees
6.2/10 (1,002 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in Southwest Illinois with star-rating
Check Southwest Illinois Hotels by Star Rating
4 Star Hotels
4 properties
Recent Southwest Illinois hotel reviews by fellow wanderers
Drury Plaza Hotel Mt. Vernon
5 out of 5
Posted 3 days ago
Travelocity Verified Review
"Everything was clean, breakfast was stupendous with tons of options, the staff were all very helpful and attentive. We had a perfect stay. "
A verified traveler stayed at Drury Plaza Hotel Mt. Vernon
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